Thermo Fisher Scientific DPP10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide: L(521) K E A I L K K K I G K P E I K I L H(539) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DPP10,uniProtId:Q8N608-1,ncbiNodeId:9606,antigenRange:521-539,antigenLength:796,antigenImageFileName:PA1-4385_DPP10_Q8N608-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4385_DPP10_Q8N608-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2093401

Product Specific Information

PA1-4385 detects DPP10 in human samples.

PA1-4385 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~75 kDa protein representing DPP10. Oligermization and differential glycosylation produces other bands as observed with other DPP family members.

PA1-4385 immunizing peptide corresponds to amino acid residues 521-539 of human DPP10.

Target Information

A novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first axons; four of which localize within the LD block strongly associated with asthma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.