Thermo Fisher Scientific AGT Monoclonal Antibody (1A10)
AGT 단백질을 인식하는 Mouse monoclonal antibody(클론 1A10). Western blot 및 ELISA에 적합하며, 인간 시료에 반응. PBS(pH 7.4) 용액 형태로 제공되며, 보존제 무첨가. -20°C에서 보관하며 동결/해동 반복은 피해야 함.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, lambda |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A10 |
| Immunogen | AGT (AAH11519, 376 a.a. ~ 485 a.a) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
TIHLTMPQLV LQGSYDLQDL LAQAELPAIL HTELNLQKLS NDRIRVGEVL NSIFFELEAD EREPTESTQQ LNKPEVLEVT LNRPFLFAVY DQSATALHFL GRVANPLSTA
Target Information
The AGT gene encodes pre-angiotensinogen (angiotensinogen precursor), a liver-expressed protein cleaved by renin in response to low blood pressure. The resulting angiotensin I is further processed by angiotensin converting enzyme (ACE) to form angiotensin II, which regulates blood pressure.
Mutations in AGT are linked to essential hypertension, renal tubular dysgenesis, atrial fibrillation, and inflammatory bowel disease.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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