Thermo Fisher Scientific NR0B1 Monoclonal Antibody (1F10)
NR0B1 단백질을 인식하는 Mouse IgG3 단클론 항체로, Western blot, ICC/IF, ELISA에 적합합니다. 인간 시료에 반응하며 GST 태그 결합 재조합 단백질을 면역원으로 사용했습니다. 액상 형태로 보존제가 없으며, -20°C에서 보관합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F10 |
| Immunogen | NR0B1 (NP_000466, 361–470 a.a.) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
IKCFLSKCWS LNISTKEYAY LKGTVLFNPD VPGLQCVKYI QGLQWGTQQI LSEHTRMTHQ GPHDRFIELN STLFLLRFIN ANVIAELFFR PIIGTVSMDD MMLEMLCTKI
Target Information
This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription mediated by the retinoic acid receptor. It also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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