Thermo Fisher Scientific Nectin 1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:1,000

Product Specifications

Product Specific Information

• Keep as concentrated solution.
• Predicted reactivity: Mouse (90%), Rat (89%), Dog (95%), Pig (96%).
• Positive Control: mouse brain, rat brain.
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes an adhesion protein involved in the organization of adherens and tight junctions in epithelial and endothelial cells.
The protein is a calcium(2+)-independent cell-cell adhesion molecule belonging to the immunoglobulin superfamily, with three extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region.
It acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus, mediating viral entry into epithelial and neuronal cells.
Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome and non-syndromic cleft lip with or without cleft palate.
Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.