Thermo Fisher Scientific AKT3 Monoclonal Antibody (66C1247.1)
AKT3 단백질을 인식하는 Mouse monoclonal antibody로, Western blot 및 Immunocytochemistry에 적합합니다. 인간, 마우스, 랫트에 반응하며, 단백질 G로 정제된 액상 형태입니다. 세포 성장, 분화, 당 대사 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:2,000 |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 66C1247.1 |
| Immunogen | A synthetic peptide corresponding to amino acid residues 119–136 (CSPTSQIDNIGEEEMDAS) of human AKT3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1070111 |
Product Specific Information
The immunogen sequence is identical in human, mouse, rat, cow, dog, and chicken.
Suggested positive control: human kidney protein or AKT3 antigen standard (transient overexpression lysate).
Target Information
AKT3 (PKB gamma) is activated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).
It is involved in key biological processes including:
- Cell proliferation and differentiation
- Apoptosis and tumorigenesis
- Glycogen synthesis and glucose uptake
Alternative splice transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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