Thermo Fisher Scientific RGS4 Polyclonal Antibody
RGS4 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western Blot 및 Immunohistochemistry에 적합하며, Human, Mouse, Rat 시료에 반응. 고순도 Protein A 정제 및 안정적인 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human RGS4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins deactivate G protein subunits of the Gi alpha, Go alpha, and Gq alpha subtypes by driving them into their inactive GDP-bound forms.
Regulator of G protein signaling 4 (RGS4) belongs to this family and shares a conserved 120-amino acid RGS domain. RGS4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. It negatively regulates signaling at or upstream of heterotrimeric G proteins and is localized in the cytoplasm.
Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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