Thermo Fisher Scientific BMP10 Polyclonal Antibody
BMP10 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성이 있으며, Protein A로 정제된 1 mg/mL 액상 형태입니다. 심장 발생 연구 등 BMP 신호 경로 분석에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human BMP10 (amino acids 350–400) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Bone morphogenetic proteins (BMPs) are part of the TGF-beta superfamily of signaling proteins involved in diverse physiological processes throughout development.
BMP-10 plays a key role in embryonic heart development by stimulating and maintaining cardiomyocyte proliferation. It signals through receptor complexes such as BMPR-1A, BMPR-1B, ALK1, ALK3, or ALK6, leading to SMAD-dependent and SMAD-independent pathways.
BMP-10 is structurally related to BMP-9, and both can inhibit endothelial cell proliferation and migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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