Thermo Fisher Scientific AMPK gamma 1/2/3 Polyclonal Antibody
AMPK gamma 1/2/3를 인식하는 Thermo Fisher의 Rabbit Polyclonal Antibody. WB, IHC, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Protein A 정제, 안정적 액상 형태로 연구용 적합.
- 카탈로그번호
- BS-9446R
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human PRKAG2/AMPK_2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The 5-AMP activated protein kinase (AMPK), a member of the SNF1 (sucrose non fermentor) kinase family, is a heterotrimeric protein composed of alpha (63 kDa), beta (30 kDa), and gamma (38 kDa) subunits.
The alpha subunit is the catalytic subunit, while beta and gamma are non-catalytic subunits that interact with the active subunit, particularly in liver tissue.
AMPK regulates fatty acid and sterol synthesis by phosphorylation of acetyl-CoA carboxylase and cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase.
AMPK is activated by AMP and can also be regulated by treatment with purified protein phosphatase in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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