Thermo Fisher Scientific ASH2L Monoclonal Antibody (6F6B9)
ASH2L 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, WB, IHC, Flow, ELISA에 적합합니다. Human 및 Mouse 반응성을 가지며, Protein G로 정제된 액상 형태입니다. 연구용으로만 사용되며, 장기 보관 시 -20°C에서 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6F6B9 |
| Immunogen | Purified recombinant fragment of human ASH2L (aa: 493–628) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898361 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
The human ASH2L gene encodes a 628 amino acid protein (isoform 1, ASH2L1) containing a nuclear localization signal and a PHD finger motif, suggesting a role as a transcription regulator.
Predicted molecular weight: 68.7 kDa. Alternative splicing may produce isoforms (~60 kDa, ~56.5 kDa).
Human ASH2L shares 60% homology with Drosophila ash2 and 90% with mouse ASH2L.
ASH2L is predominantly expressed in adult heart and testis, and fetal lung and liver, with minimal expression in adult lung, liver, kidney, prostate, and peripheral leukocytes.
It is associated with leukemia cell lines (K562, Hel, Dami) and plays a role in hematopoiesis.
ASH2L may interact with beta-tubulin and beta-catenin.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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