
Thermo Fisher Scientific Cadherin 17/LI Cadherin (Liver-Intestine Marker) Monoclonal Antibody (CDH17/2618)
인체 CDH17 단백질을 인식하는 마우스 단클론 항체로, 간·장 조직의 면역조직화학 분석에 적합합니다. IHC 및 유세포분석에 사용 가능하며, 단백질 A로 정제된 액상형 비결합 항체입니다. 4°C에서 보관하며 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CDH17/2618 |
| Immunogen | Recombinant fragment (around aa 242–418) of human Cadherin 17 protein (CDH17) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CDH17 gene is a member of the cadherin superfamily, encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region with seven cadherin domains and a transmembrane region but lacking the conserved cytoplasmic domain. It is expressed in the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter involved in the absorption of peptide-based drugs. It may also contribute to the morphological organization of the liver and intestine. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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