Thermo Fisher Scientific Cadherin 17/LI Cadherin (Liver-Intestine Marker) Monoclonal Antibody (CDH17/2617)
Cadherin 17 단백질을 인식하는 마우스 단클론 항체로, 간·소장 조직 마커로 사용됩니다. Western blot, IHC 등 다양한 응용에 적합하며, 고순도의 Protein A 정제 항체입니다. PBS 용액에 보존되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CDH17/2617 |
| Immunogen | Recombinant fragment (around aa 242–418) of human Cadherin 17 protein (CDH17) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CDH17 gene belongs to the cadherin superfamily, which encodes calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, featuring an extracellular region with seven cadherin domains and a transmembrane region but lacking the conserved cytoplasmic domain. It is primarily expressed in the gastrointestinal tract and pancreatic ducts, functioning as an intestinal proton-dependent peptide transporter involved in the absorption of peptide-based drugs. CDH17 may also contribute to the morphological organization of the liver and intestine. Alternative splicing results in multiple transcript variants.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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