Thermo Fisher Scientific Cadherin 17/LI Cadherin (Liver-Intestine Marker) Monoclonal Antibody (CDH17/2618)
인체 CDH17 단백질을 인식하는 마우스 단클론 항체로, 간 및 장 조직 마커 연구에 적합. IHC, Flow Cytometry, Peptide Array에 사용 가능. 단백질 A 정제, 보존제 무첨가 PBS 용액 형태. -20°C 보관, 동결-해동 반복 피해야 함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CDH17/2618 |
| Immunogen | Recombinant fragment (around aa 242–418) of human Cadherin 17 (CDH17) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CDH17 gene belongs to the cadherin superfamily, encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein has seven cadherin domains and a transmembrane region but lacks the conserved cytoplasmic domain. It is expressed in the gastrointestinal tract and pancreatic ducts, functioning as an intestinal proton-dependent peptide transporter involved in the absorption of peptide-based drugs. It may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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