Thermo Fisher Scientific BMP-3 Polyclonal Antibody
Rabbit polyclonal antibody against human BMP-3 for WB and ICC/IF applications. High purity (>95%) via antigen affinity chromatography. Supplied in PBS with glycerol, 1 mg/mL concentration. Suitable for research use only.
- 카탈로그번호
- PA575488
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 329–374 of Human BMP-3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719216 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Bone morphogenetic proteins (BMPs) belong to the TGF-β superfamily. They stimulate the production of bone matrix proteins and influence stromal cell and osteoclast proliferation, key steps in bone marrow development. In addition to promoting ectopic bone and cartilage formation, BMPs regulate growth, differentiation, chemotaxis, proliferation, and apoptosis in various cell types, including mesenchymal, epithelial, hematopoietic, and neuronal cells. BMPs also play roles in dorsal/ventral patterning. BMP3, highly expressed in lung, ovary, and small intestine, participates in cartilage and bone formation. BMP3 and BMP2 genes map to conserved regions between human and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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