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Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), PerCP-eFluor 710, eBioscience
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Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), PerCP-eFluor 710, eBioscience

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마우스 Ly-6G(Gr-1)에 특이적인 단클론 항체로, PerCP-eFluor 710 형광체 결합. Flow Cytometry에 최적화되어 있으며, 0.125 µg/test 사용 권장. 4°C 암소 보관, 광민감성 주의. 연구용으로만 사용 가능.

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46-9668-8x (2개 옵션)
판매단위
pk
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마지막 업데이트 2025. 08. 05. 오후 05:41
Thermo Fisher Scientific 46-9668-82 Ly-6G Monoclonal Antibody (1A8-Ly6g), PerCP-eFluor 710, eBioscience 100 ug pk판매 단위 pk ·
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537,700원VAT 포함 591,470원
Thermo Fisher Scientific 46-9668-80 Ly-6G Monoclonal Antibody (1A8-Ly6g), PerCP-eFluor 710, eBioscience 25 ug pk판매 단위 pk ·
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186,800원VAT 포함 205,480원

Thermo Fisher Scientific · Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), PerCP-eFluor 710, eBioscience

Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), PerCP-eFluor 710, eBioscience

Applications

  • Flow Cytometry (Flow)

Tested Dilution: 0.125 µg/test
View 30 publications


Product Specifications

항목 내용
Species Reactivity Mouse
Published species Mouse
Host / Isotype Rat / IgG2a, kappa
Recommended Isotype Control Rat IgG2a kappa Isotype Control (eBR2a), PerCP-eFluor™ 710, eBioscience™
Class Monoclonal
Type Antibody
Clone 1A8-Ly6g
Conjugate PerCP-eFluor™ 710
Excitation / Emission Max 482 / 708 nm
Form Liquid
Concentration 0.2 mg/mL
Purification Affinity chromatography
Storage buffer PBS, pH 7.2
Contains 0.09% sodium azide
Storage conditions 4°C, store in dark, DO NOT FREEZE!
Shipping conditions Ambient (domestic); Wet ice (international)
RRID AB_2573892

Additional Formats Available

  • Alexa Fluor 700
  • APC
  • APC-eFluor 780
  • Biotin
  • Brilliant UV 395 / 563 / 661 / 737
  • Brilliant Violet 421 / 480 / 650 / 786
  • eFluor 450
  • FITC
  • Functional Grade
  • PE / PE-Cyanine5 / PE-Cyanine7 / PE-eFluor 610
  • Super Bright 436 / 600 / 702
  • Request custom conjugation

Product Specific Information

The monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G (Gr-1), a 25-kDa GPI protein expressed exclusively by neutrophils. It plays a role in neutrophil infiltration, recruitment, and migration, and associates with B2 integrins CD11a/CD11b.

Unlike RB6-8C5, 1A8-Ly6g binds only to Ly-6G on neutrophils and has been used to deplete neutrophils with reported antagonist activity.

Applications Reported: Flow cytometric analysis
Applications Tested: Tested on mouse bone marrow cells at ≤0.125 µg/test (100 µL final volume, 10⁵–10⁸ cells/test). Optimal titration recommended.

Fluorochrome: PerCP-eFluor® 710

  • Excitation: 488 nm (Blue Laser)
  • Emission: 710 nm
  • Recommended filter: 710/50 bandpass (695/40 acceptable)
  • Light sensitive: Protect from light
  • Fixation: Compatible with IC Fixation Buffer (Product #00-8222) or 1-step Fix/Lyse Solution (Product #00-5333)
  • Storage after fixation: Up to 3 days at 4°C in dark
  • Filtration: 0.2 µm post-manufacturing filtered

Target Information

Ly6G (Lymphocyte antigen 6 complex locus G6D)

  • Component of myeloid differentiation antigen Gr-1 (with Ly6C)
  • Molecular weight: ~21–25 kDa
  • Expressed in bone marrow myeloid cells
  • Marker for neutrophils, monocytes, granulocytes
  • Involved in granulocyte differentiation and maturation
  • Suggested role in anti-tumor response and modulation of local immune activity

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.


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