Thermo Fisher Scientific Stargazin Monoclonal Antibody (N245/36)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

1:100

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

N245/36

Immunogen

Fusion protein amino acids 203-323 (Cytoplasmic C-terminus) of rat TARPGamma2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Stargazin,uniProtId:Q71RJ2-1,ncbiNodeId:10114,antigenRange:203-323,antigenLength:323,antigenImageFileName:MA5-27645_Stargazin_Q71RJ2-1_House_mouse.svg,antigenImageFileNamePDP:MA5-27645_Stargazin_Q71RJ2-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2735374

Product Specific Information

1 µg/mL of MA5-27645 was sufficient for detection of TARP Gamma2/4/8 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.|Detects approximately 35-55kDa. Does not cross-react with TARPGamma3.

This antibody was formerly sold as clone S245-36.

Target Information

Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.