Thermo Fisher Scientific PERP Recombinant Rabbit Monoclonal Antibody (JU04-51)
PERP 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot 및 IHC(P)에서 검증됨. HEK293 세포 발현, Protein A 정제. 인간 시료 반응성, 1 mg/mL 농도. -20°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JU04-51 |
| Immunogen | Synthetic peptide within Human PERP aa 144–193 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848526 |
Product Specific Information
Positive Control: Human skin tissue, mouse small intestine tissue.
Target Information
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in the p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP, and PERP, have been identified. PERP (also known as PIGPC1 or THW) is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates the PERP gene; the translated PERP protein mediates p53-induced apoptosis. The expression of PERP causes cell death and functions as a mediator of p53-induced apoptosis. PERP shows sequence similarity to PMP-22/gas3 and is a member of the PMP-22/gas3 family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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