Thermo Fisher Scientific Bcl10 Polyclonal Antibody
Bcl10 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot과 Immunoprecipitation에 적합하며, 1 mg/mL 농도의 액상 형태로 제공. 4°C 보관, 1년 권장 유효기간. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 183 and 233 of human B-cell CLL/lymphoma 10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK.
BCL-10 acts as an adapter protein between the upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex, and is a substrate for MALT1.
Mutations in the gene can lead to Immunodeficiency 37 or mucosa-associated lymphoid type lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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