Thermo Fisher Scientific IFN beta Polyclonal Antibody
IFN beta 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Human 및 Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 5 µg/mL | 2 publications |
| Immunohistochemistry (IHC) | - | 7 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2.5 µg/mL | 1 publication |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 20 µg/mL | - |
| Immunohistochemistry (Frozen) (IHC (F)) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | 20 µg/mL | 1 publication |
| Flow Cytometry (Flow) | - | 1 publication |
| ELISA | - | 2 publications |
| Miscellaneous PubMed (Misc) | - | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid peptide from near the center of human IFN-β |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155641 |
Product Specific Information
- A suggested positive control is A-20 cell lysate.
- PA5-20390 can be used with blocking peptide PEP-0507.
Target Information
Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by natural IFN-producing cells (IPCs) as part of the host immune response.
IFNs can also inhibit tumor development.
IFN-beta binding activates tyrosine kinases Jak1 and Tyk2, leading to phosphorylation of STAT transcription factors and induction of immune response genes.
Members of the toll-like receptor (TLR) family also stimulate IFN-beta production.
Clinically, IFN-beta is used in the treatment of tumors, infections, and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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