Thermo Fisher Scientific ROBO1 Polyclonal Antibody
ROBO1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간, 마우스, 랫트에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 저장 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human ROBO1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719542 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
Specialized midline cells in the central nervous system (CNS) guide axonal growth by producing cues such as nectins and slit, which act as attractants and repellents. Robo proteins serve as receptors for the repellent Slit and play a key role in axon guidance. Non-crossing axons express high levels of Robo, while crossing axons show dynamic expression changes before and after crossing the midline. Robo1 and Robo2 are human homologs of the Drosophila Roundabout protein, with Robo1 also homologous to the C. elegans gene sax3 and Robo2 to the zebrafish gene astray.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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