Thermo Fisher Scientific GNPDA1 Polyclonal Antibody
Thermo Fisher Scientific의 GNPDA1 Polyclonal Antibody는 인간 GNPDA1 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot, IHC, ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GNPDA1. Recombinant protein control fragment (Product #RP-93678). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789036 |
Product Specific Information
Immunogen sequence:
EHYSQASEWA AKYIRNRIIQ FNPGPEKYFT LGLPTGSTPL GCYKKLIEYY KNGDLSFKYV KTFNMDEYVG LPRDHPESYH SFMWNNFFKH IDIHPENTHI LDGNAVDLQA ECDAFEEKIK AA
Target Information
GNPDA1 is a 289 amino acid cytoplasmic protein belonging to the glucosamine/galactosamine-6-phosphate isomerase family. It is one of the two mammalian glucosamine-6-phosphate deaminase enzymes.
GNPDA1 catalyzes the reversible conversion of D-glucosamine-6-phosphate (GlcN6P) into D-fructose-6-phosphate (Fru6P) and ammonium through an aldo/keto isomerization and amination/deamination process.
It may trigger calcium oscillations in mammalian eggs at fertilization, influencing egg and early embryo development.
GNPDA1 forms a homohexamer and is ubiquitously expressed in most human tissues, with high expression in testis, ovary, placenta, and heart, as well as in various cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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