Thermo Fisher Scientific ATR Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.03-0.07 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to a portion of human Ataxia and Rad3 related encoded within exon 5.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

tris phosphate/tris citrate, pH 7-8

Contains

0.1% Sodium azide

Storage conditions

4° C, do not freeze

Shipping conditions

Wet ice

RRID

AB_557669

Product Specific Information

Recommended positive controls: Whole cell lysate from HeLa and U2OS cells.

Target Information

The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.