Thermo Fisher Scientific ATR Polyclonal Antibody
Thermo Fisher Scientific의 ATR Polyclonal Antibody는 인간 및 생쥐 시료에 반응하는 rabbit IgG 기반 항체입니다. DNA 손상 반응 연구에 적합하며 Western blot에서 0.03–0.07 µg/mL 농도로 사용 가능합니다. 항원 친화 크로마토그래피로 정제된 고품질 액상 항체로, 안정적인 4°C 보관이 가능합니다.
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Thermo Fisher Scientific ATR Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.03–0.07 µg/mL
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a portion of human Ataxia and Rad3 related encoded within exon 5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris phosphate / Tris citrate, pH 7–8 |
| Contains | 0.1% Sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_557669 |
Product Specific Information
Recommended positive controls: Whole cell lysate from HeLa and U2OS cells.
Target Information
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. It can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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