Thermo Fisher Scientific CDH3 Monoclonal Antibody (OTI2D5), TrueMAB
인간 CDH3(P-cadherin)을 인식하는 Mouse IgG2a 단클론 항체. Western blot, IHC, ICC/IF에 적합하며 고순도 친화 크로마토그래피 정제. 무보존제, 동결건조 형태로 안정적 저장 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D5 |
| Immunogen | Full length human recombinant protein of human CDH3 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
P-cadherin (Cadherin-3) is a Type 1 cadherin protein belonging to the cadherin superfamily. These calcium-dependent cell-cell adhesion glycoproteins are involved in development, wound healing, signaling, cell growth, and differentiation.
P-cadherin is expressed in fetal tissues and adult epithelial structures such as the basal layer of epidermis, breast, prostate, ovary, cervix, hair follicle, and corneal endothelium.
Overexpression is linked to poor prognosis in various carcinomas (breast, prostate, ovary, colon, stomach). Mutations in CDH3 are associated with congenital hypotrichosis with juvenile macular dystrophy.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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