Thermo Fisher Scientific CEA Monoclonal Antibody (C365D3(NCRC23)), FITC
CEA(CD66e) 인식하는 FITC 결합 단일클론 항체로 유세포분석(Flow Cytometry)에 적합. 인간 시료 반응성, Mouse IgG1 아이소타입. 단백질 A로 정제, PBS/BSA 완충액에 보관. 4°C 단기, -20°C 장기 보관 권장.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: Neat–1:10
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C365D3 (NCRC23) |
| Immunogen | Proprietary Immunogen |
| Conjugate | FITC (Fluorescein) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_929263 |
Product Specific Information
For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
Mouse anti-Human CD66e antibody, clone C365D3 (NCRC23), recognizes human Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), also known as CD66e, carcinoembryonic antigen, Meconium antigen 100, or CEA.
Target Information
CEA (Carcinoembryonic Antigen, CD66e) is synthesized during fetal gut development and re-expressed in increased amounts in intestinal carcinomas and other tumors.
It belongs to the immunoglobulin supergene family and consists of one N domain and six immunoglobulin constant-like A (A1, A2, A3) and B (B1, B2, B3) domains.
CEA antibodies are useful for identifying metastatic adenocarcinoma origins and distinguishing pulmonary adenocarcinomas (60–70% CEA+) from pleural mesotheliomas (rarely or weakly CEA+).
CEA functions as a cell adhesion molecule and is involved in tissue organization, angiogenesis, apoptosis, tumor suppression, metastasis, and immune modulation.
Multiple transcript variants encoding different isoforms have been reported, though not all full-length variants are defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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