Thermo Fisher Scientific PPP1R8 Monoclonal Antibody (OTI1E9), TrueMAB
PPP1R8 단백질을 인식하는 Mouse Monoclonal Antibody로 Western blot에 적합. Human 종에 반응하며, Lyophilized 형태로 제공됨. Affinity chromatography로 정제되어 높은 특이성과 순도를 보유. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–225 of human PPP1R8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The PPP1R8 gene produces three isoforms via alternative splicing.
- Two isoforms act as specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA.
- The third isoform functions as a single-strand endoribonuclease similar to RNase E of E. coli, requiring magnesium and cleaving A+U-rich RNA regions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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