Thermo Fisher Scientific LGALS3 Monoclonal Antibody (OTI2F1), TrueMAB
인간 LGALS3 단백질을 타겟으로 하는 Mouse IgG2b 단클론 항체. Western blot 및 파라핀 절편 면역조직화학(IHC) 검증 완료. 동결건조 형태로 제공되며, 재구성 및 접합 실험에 적합. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F1 |
| Immunogen | Full length human recombinant protein of human LGALS3 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL distilled water to achieve ~1 mg/mL antibody concentration.
- For conjugation experiments, perform additional desalting (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Galactose-specific lectin that binds IgE. May mediate alpha-3, beta-1 integrin-dependent stimulation by CSPG4 for endothelial cell migration. Along with DMBT1, it is required for terminal differentiation of columnar epithelial cells during early embryogenesis. Acts as a pre-mRNA splicing factor in the nucleus. Involved in acute inflammatory responses such as neutrophil activation and adhesion, monocyte/macrophage chemoattraction, opsonization of apoptotic neutrophils, and mast cell activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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