Thermo Fisher Scientific ZNF281 Polyclonal Antibody
Rabbit polyclonal antibody against ZNF281. Recognizes amino acids 775–825 of human ZNF281. Supplied as liquid, 1 mg/mL, unconjugated. Store at 4°C, ships on wet ice. For research use only.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between amino acids 775 and 825 of human ZNF281 (UniProt ID: Q9Y2X9-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
ZFP281 (also known as ZBP-99) is a member of a conserved family of transcription factors that interact with GC-rich promoters.
It contains four Kruppel-like zinc fingers and is highly homologous to ZBP-89, another regulator of ornithine decarboxylase gene expression.
ZFP281 interacts with transcription factors such as Sp1 to repress vimentin gene transcription and regulates embryonic stem cell pluripotency by directly controlling specific target genes.
It physically interacts with transcription factors POU5F1, Sox2, and NANOG.
Gene expression microarray analysis indicates that ZFP281 can both activate and repress target genes, demonstrating its bifunctional role in stem cell gene regulation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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