Thermo Fisher Scientific TCR V beta F1 Monoclonal Antibody (8A3)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

View 3 publications 3 publications

Immunohistochemistry (IHC)

-

View 37 publications 37 publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

View 6 publications 6 publications

Immunocytochemistry (ICC/IF)

-

View 2 publications 2 publications

Flow Cytometry (Flow)

2 µg/test

View 4 publications 4 publications

ELISA (ELISA)

-

View 2 publications 2 publications

Immunoprecipitation (IP)

Assay-dependent

View 2 publications 2 publications

ChIP assay (ChIP)

-

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

-

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse, Non-human primate, Yeast

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

8A3

Immunogen

Human TCR ß chain constant region

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.15 mg/mL

Purification

Protein G

Storage buffer

PBS with 0.5% BSA

Contains

0.1% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_223502

Product Specific Information

TCR1151 targets TCR Beta F1 in FACS, FISH, IHC, IHC(P), IP, and WB applications and shows reactivity with Human samples.

The TCR1151 immunogen is human TCR ß chain constant region.

TCR1151 detects TCR Beta F1 which has a predicted molecular weight of approximately 13 kDa.

Target Information

The T Cell Receptor alpha beta (TCRab) is a heterodimeric membrane receptor that consists of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 proteins. TCRab participates in the activation of T-cells in response to an antigen presented in the context of MHC. Engagement of the TCRab initiates signaling cascades that ultimately result in cellular proliferation, differentiation, cytokine production, and/or activation-induced cell death. These signaling cascades regulate T-cell development, homeostasis, activation, acquisition of effector functions and apoptosis. Cells expressing TCRab constitute the vast majority of T cells in both human and mouse.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.