Thermo Fisher Scientific TCR V beta F1 Monoclonal Antibody (8A3)
인간 TCR Beta F1 단백질을 표적하는 Mouse IgG1 모노클로날 항체로 다양한 면역분석(WB, IHC, Flow 등)에 사용 가능. Protein G로 정제된 액상 형태로 제공되며, 높은 특이성과 재현성을 보장. 연구용으로만 사용.
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Thermo Fisher Scientific TCR V beta F1 Monoclonal Antibody (8A3)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | 3 publications |
| Immunohistochemistry (IHC) | - | 37 publications |
| Immunohistochemistry (Paraffin) (IHC(P)) | Assay-dependent | 6 publications |
| Immunocytochemistry (ICC/IF) | - | 2 publications |
| Flow Cytometry (Flow) | 2 µg/test | 4 publications |
| ELISA | - | 2 publications |
| Immunoprecipitation (IP) | Assay-dependent | 2 publications |
| ChIP assay (ChIP) | - | 1 publication |
| Miscellaneous PubMed (Misc) | - | 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse, Non-human primate, Yeast |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8A3 |
| Immunogen | Human TCR ß chain constant region |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.5% BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_223502 |
Product Specific Information
TCR1151 targets TCR Beta F1 in FACS, FISH, IHC, IHC(P), IP, and WB applications and shows reactivity with human samples.
The TCR1151 immunogen is the human TCR ß chain constant region.
TCR1151 detects TCR Beta F1, which has a predicted molecular weight of approximately 13 kDa.
Target Information
The T Cell Receptor alpha beta (TCRab) is a heterodimeric membrane receptor composed of variable alpha and beta chains, expressed as part of a complex with CD3 proteins.
TCRab mediates T-cell activation in response to antigens presented by MHC molecules, initiating signaling cascades that regulate cellular proliferation, differentiation, cytokine production, and activation-induced cell death.
These cascades are essential for T-cell development, homeostasis, activation, effector function acquisition, and apoptosis.
Cells expressing TCRab constitute the majority of T cells in both human and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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