Thermo Fisher Scientific SLC29A3 Polyclonal Antibody
SLC29A3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 실험에 적합합니다. Human, Mouse, Rat 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 냉장 보관(2–8°C) 가능하며, 장기 보관 시 -20°C 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 19 amino acid peptide near the amino terminus of human SLC29A3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2554643 |
Product Specific Information
- Recommended positive control: Mouse bladder tissue lysate
- Detects both known isoforms of SLC29A3
- Not expected to cross-react with other SLC29 proteins
Target Information
SLC29A3 is a member of the equilibrative nucleoside transporter family, playing a key role in nucleoside and nucleobase uptake for nucleotide synthesis salvage pathways. It is a transmembrane glycoprotein localized to the lysosomal membrane and functions as a broad selectivity, low-affinity nucleoside transporter.
Mutations in the SLC29A3 gene are associated with H syndrome, characterized by cutaneous hyperpigmentation, hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism.
A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been linked to mutations at this locus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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