Thermo Fisher Scientific BAF53A Polyclonal Antibody
BAF53A 단백질을 표적하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 ChIP assay에 사용 가능하며, KLH 결합 합성 펩타이드(50–150 aa)를 면역원으로 제작되었습니다. 항원 친화 크로마토그래피로 정제된 고품질 시약입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
ChIP assay (ChIP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 50–150 of Human BAF53A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10985597 |
Product Specific Information
PA5-19421 targets BAF53A in IF, IHC(F), and WB applications and shows reactivity with Human, Mouse, and Rat samples.
The immunogen is a synthetic peptide conjugated to KLH derived from residues 50–150 of Human BAF53A.
Detects BAF53A with a predicted molecular weight of approximately 53 kDa.
Target Information
BAF53A is a member of actin-related proteins (ARPs), sharing significant sequence identity with conventional actins.
ARPs and actins both have an actin fold, an ATP-binding cleft, as a common feature.
ARPs are involved in cellular processes such as vesicular transport, spindle orientation, nuclear migration, and chromatin remodeling.
BAF53A encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex, related to the SWI/SNF complex in yeast and Drosophila.
Together with beta-actin, it is required for maximal ATPase activity of BRG1 and for association of the BAF complex with chromatin/matrix.
Three transcript variants encoding two different protein isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-19421_BAF53A_O96019-1_Rabbit.svg, PA5-19421_BAF53A_O96019-1_Rabbit_PDP.jpeg)
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