Thermo Fisher Scientific USP15 Polyclonal Antibody
USP15 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응합니다. Immunohistochemistry (Paraffin)에서 1:50~1:200 희석 비율로 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며 PBS와 40% glycerol 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA511xxxx (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific USP15 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human USP15 (control fragment Product #RP-89264) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856117 |
Product Specific Information
Immunogen sequence:
IFAMDENLSS IMERDDIYVF EININRTEDT EHVIIPVCLR EKFRHSSYTH HTGSSLFGQP FLMAVPRNNT EDKLYNLLLL RMCRYVKIST ETEETEGSLH CCKDQNINGN GPNGIHEEGS PSEMETD
Target Information
Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26S proteasome are coupled to multiple copies of ubiquitin. Attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. Deubiquitination is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families:
- Ubiquitin C-terminal hydrolases
- Ubiquitin-specific processing proteases (USPs)
- OTU-domain ubiquitin-aldehyde-binding proteins
- Jab1/Pad1/MPN-domain-containing metallo-enzymes
Among these, USPs are the most widespread deubiquitinating enzymes across evolution. They release ubiquitin from conjugated proteins and contain conserved Cys and His catalytic domains, with variable terminal extensions that aid in substrate recognition, localization, and protein interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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