Thermo Fisher Scientific CD148 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human CD148. Recombinant protein control fragment (Product #RP-102094). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD148,uniProtId:Q12913-1,ncbiNodeId:9606,antigenRange:667-812,antigenLength:1337,antigenImageFileName:PA5-110703_CD148_Q12913-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110703_CD148_Q12913-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856114

Product Specific Information

Immunogen sequence: SSNATQVVTD IGITDATVTE LIPGSSYTVE IFAQVGDGIK SLEPGRKSFC TDPASMASFD CEVVPKEPAL VLKWTCPPGA NAGFELEVSS GAWNNATHLE SCSSENGTEY RTEVTYLNFS TSYNISITTV SCGKMAAPTR NTCTTG

Target Information

CD148 is a highly glycosylated transmembrane protein of up to 250 kDa, containing eight fibronectin type III domains in the extracellular region and one tyrosine phosphatase domain in the cytoplasmic region. Expression is found broadly on fibroblasts, epithelial cells, lymphocytes (B, T and NK cells), and myeloid cells (monocytes and granulocytes). CD148 can dephosphorylate proteins such as LAT and PLC-gamma, and is involved in the downregulation of T cell activation. Conversely, CD148 expression can be upregulated following T cell activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.