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ELK Biotechnology Ku-70 (phospho Ser5) rabbit pAb
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Ku-70 (phospho Ser5) rabbit pAb는 인산화된 Ku70 단백질을 검출하는 폴리클로날 항체입니다. WB, IHC, IF, ELISA에 적합하며 인간 및 마우스 시료에 반응합니다. DNA 손상 복구 연구 및 세포핵 단백질 분석에 유용합니다.
- 판매단위
- pk
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ELK Biotechnology ES5420-100UL Ku-70 (phospho Ser5) rabbit pAb, 100UL pk판매 단위 pk ·
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ELK Biotechnology ES5420-50UL Ku-70 (phospho Ser5) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Ku-70 (phospho Ser5) rabbit pAb
제품명
Ku-70 (phospho Ser5) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box- |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Ku70 around the phosphorylation site of Ser5. AA range: 1-50 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 70 kDa |
| Gene ID (Human) | 2547 |
| Human Swiss-Prot No | P12956 |
| Cellular Localization | Nucleus; Chromosome |
| Species Reactivity | Human; Mouse |
Background
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. It may be involved in the repair of nonhomologous DNA ends required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. (provided by RefSeq, Jul 2008)
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