Thermo Fisher Scientific PLEKHM3 Polyclonal Antibody
Human, Mouse, Rat 반응성의 Rabbit Polyclonal 항체로 Western blot, IHC, ICC/IF에 적합. Recombinant Human PLEKHM3 면역원 기반으로 제작되었으며, 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PLEKHM3 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PLEKHM3. Recombinant protein control fragment (Product #RP-96208). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645668 |
Product Specific Information
Immunogen sequence:
MIWDHCKSRL LETKAQNVFP AKEQFMVQRG TTPDNLSWME QKEASTFNFF NICQRRRDRP RSVNDLLDET STFKPGHARS RSDITQVD
Highest antigen sequence identity to the following orthologs:
- Mouse: 93%
- Rat: 94%
Target Information
PLEKHM3 (also known as DAPR) is a member of the M family of Pleckstrin homology domain-containing proteins. It was identified through chromatin immunoprecipitation and CpG microarray analysis examining proteins regulated by myocyte-enhancing factor 2.
In C2C12 myoblast cells, PLEKHM3 binds to PI3K signaling member protein kinase B in the cytosol prior to differentiation into myotubes. Upon differentiation, PLEKHM3 localizes to membrane fractions.
RNAi-mediated knockdown of PLEKHM3 inhibits myotube formation, indicating its essential role in myoblast differentiation during myogenesis.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.