Thermo Fisher Scientific ETAA1 Polyclonal Antibody
Human ETAA1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% 글리세롤) 용액 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ETAA1. Recombinant protein control fragment (Product # RP-102644) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641133 |
Product Specific Information
Immunogen sequence:
INNNSEHGAK NMFAISKQGS NLVQSKHLNP GSISVQTSLT NSSQIDKPMK MEKGEMYGNS PRFLGATNLT MYSKISNCQI NNLHVSYTNT DVPIQVN
Highest antigen sequence identity to the following orthologs:
- Mouse: 36%
- Rat: 44%
Target Information
ETAA1 (Ewing’s tumor-associated antigen 1), also known as ETAA16, is a 926 amino acid cytoplasmic protein highly expressed in kidney, brain, liver, and Ewing tumor cell lines.
ETAA1 undergoes post-translational phosphorylation following DNA damage, likely mediated by ATM or ATR, and may function as a tumour-specific cell surface antigen in Ewing’s family tumour cell lines.
The ETAA1 gene is located on human chromosome 2, which contains approximately 237 million bases, over 1,400 genes, and represents about 8% of the human genome.
Mutations in genes on chromosome 2 are associated with several disorders, including Harlequin ichthyosis, sitosterolemia, and Alstrom syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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