Thermo Fisher Scientific ETAA1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ETAA1. Recombinant protein control fragment (Product #RP-102644). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ETAA1,uniProtId:Q9NY74-1,ncbiNodeId:9606,antigenRange:668-764,antigenLength:926,antigenImageFileName:PA5-57129_ETAA1_Q9NY74-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57129_ETAA1_Q9NY74-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641133

Product Specific Information

Immunogen sequence: INNNSEHGAK NMFAISKQGS NLVQSKHLNP GSISVQTSLT NSSQIDKPMK MEKGEMYGNS PRFLGATNLT MYSKISNCQI NNLHVSYTNT DVPIQVN

Highest antigen sequence identity to the following orthologs: Mouse - 36%, Rat - 44%.

Target Information

ETAA1 (Ewings tumor-associated antigen 1), also known as ETAA16, is a 926 amino acid cytoplasmic protein that is highly expressed in kidney, brain, liver and Ewing tumor cell lines. ETAA1 undergoes post-translational phosphorylation following DNA damage, most likely by either ATM or ATR, and is suggested to function as a tumour-specific cell surface antigen in Ewings family of tumour cell lines. The gene encoding ETAA1 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstrom syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.