Thermo Fisher Scientific VIM Monoclonal Antibody (OTI5C10), Biotin, TrueMAB
Human Vimentin 단백질을 인식하는 Mouse IgG1 단클론 항체로, Biotin으로 표지되어 ELISA 및 Luminex 분석에 사용 가능. 고순도 Affinity chromatography 정제, 안정적인 PBS/BSA/glycerol buffer 구성. 연구용으로만 사용.
- 판매단위
- pk
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Applications
ELISA (ELISA)
- Tested Dilution: 1:250–1:1,000
Luminex (LUM)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C10 |
| Immunogen | Full length human recombinant protein of human VIM produced in HEK293T cell |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved in intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed along with desmin during early cellular development, and later replaced by tissue-specific IFPs.
Vimentin has been implicated in steroid synthesis regulation via its role as a storage network for cholesterol-containing lipid droplets. Phosphorylation of vimentin by protein kinase leads to filament breakdown and activation of contractile events, facilitating lipid droplet interaction with mitochondria and enhancing steroid synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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