Thermo Fisher Scientific SMPD1 Monoclonal Antibody (OTI10C5), TrueMAB
인간 SMPD1 단백질(아미노산 62-341)에 특이적인 단클론 항체로 Western blot에 적합. 마우스 IgG1 형식의 TrueMAB 제품이며, 보존제 없이 동결건조 상태로 제공. 연구용으로만 사용 가능하며 Niemann-Pick 질환 관련 단백질 연구에 활용 가능.
- 판매단위
- pk
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Thermo Fisher Scientific SMPD1 Monoclonal Antibody (OTI10C5), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution
- 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 62-341 of human SMPD1 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The SMPD1 gene encodes lysosomal acid sphingomyelinase, which converts sphingomyelin to ceramide and also exhibits phospholipase C activity.
Defects in this gene cause Niemann-Pick disease type A (NPA) and type B (NPB).
Three transcript variants encoding two different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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