Thermo Fisher Scientific CD69 Monoclonal Antibody (H1.2F3), APC, eBioscience

Thermo Fisher Scientific CD69 Monoclonal Antibody (H1.2F3), APC, eBioscience

Applications

• Flow Cytometry (Flow)
  Tested dilution: 0.25 µg/test
  View 87 publications

Product Specifications

Additional Formats

• Unconjugated
• Alexa Fluor 700
• APC-eFluor 780
• Biotin
• Brilliant UV 496
• Brilliant UV 661
• Brilliant UV 737
• Brilliant Violet 421
• Brilliant Violet 786
• eFluor 450
• FITC
• Functional Grade
• PE
• PE-Cyanine5
• PE-Cyanine7
• PE-eFluor 610
• PerCP-Cyanine5.5
• Super Bright 436
• Super Bright 600
• Super Bright 645
• Request custom conjugation

Product Specific Information

The H1.2F3 monoclonal antibody reacts with mouse CD69, also known as very early activation antigen (VEA). CD69 (~35 kDa) is expressed as a disulfide-linked dimer on the cell surface. Activation of T and B cells rapidly upregulates CD69, indicating its role in lymphocyte activation and development.

• Applications Reported: Flow cytometric analysis
• Applications Tested: Tested on stimulated mouse splenic cell cultures; ≤0.25 µg/test (100 µL final volume, 10⁵–10⁸ cells/test)
• Recommended: Titrate for optimal performance
• Excitation: 633–647 nm
• Emission: 660 nm
• Laser: Red Laser
• Filtration: 0.2 µm post-manufacturing filtered

Target Information

CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide-bonded homodimer (~60 kDa under non-reducing conditions). It contains N-linked oligosaccharides and is found on activated platelets. CD69 is involved in lymphocyte signal transduction and proliferation, and may transmit signals in NK cells and platelets.
Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.
Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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