Thermo Fisher Scientific VEGF Monoclonal Antibody (VG1)
인간 VEGF를 표적으로 하는 단클론 항체로, WB, IHC(P), ICC/IF 등 다양한 응용에 적합합니다. 고순도 Protein A/G 정제 방식으로 제조되었으며, 4°C에서 안정적으로 보관 가능합니다. 혈관신생 및 종양 연구에 활용되는 연구용 항체입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 7 publications |
| Immunohistochemistry (IHC) | – | View 46 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 | View 4 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:40–1:200 | View 3 publications |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse, Rabbit, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VG1 |
| Immunogen | Recombinant VEGF189 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | 10 mM PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10980775 |
Product Specific Information
MA5-12184 targets Vascular Endothelial Growth Factor (VEGF) in IF, IHC (P), and WB applications and shows reactivity with Human samples.
Target Information
VEGF (vascular endothelial growth factor) is a 45 kDa homodimeric, disulfide-linked glycoprotein involved in angiogenesis, promoting tumor progression and metastasis. It affects vascular endothelium by enhancing cell viability, mitogenesis, chemotaxis, and permeability.
The VEGF family includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. These proteins regulate angiogenesis through receptors FLT1 (VEGFR-1) and FLK1/KDR (VEGFR-2), primarily expressed in endothelial cells.
Elevated VEGF levels are associated with POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy, Skin changes), also known as Crow-Fukase syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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