Thermo Fisher Scientific Stabilin 2 Polyclonal Antibody
Stabilin 2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에서 반응합니다. Western blot 및 ELISA에 적합하며, 고순도의 Affinity Chromatography 정제 제품입니다. 세포막 및 세포질 단백질 검출 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1550–1850 of human STAB2 (NP_0600349) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.52 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804293 |
Product Specific Information
Immunogen sequence:
GKVCTLINVC LTKNGGCSEF AICNHTGQVE RTCTCKPNYI GDGFTCRGSI YQELPKNPKT SQYFFQLQEH FVKDLVGPGP FTVFAPLSAA FDEEARVKDW DKYGLMPQVL RYHVVACHQL LLENLKLISN ATSLQGEPIV ISVSQSTVYI NNKAKIISSD IISTNGIVHI IDKLLSPKNL LITPKDNSGR ILQNLTTLAT NNGYIKFSNL IQDSGLLSVI TDPIHTPVTL FWPTDQALHA LPAEQQDFLF NQDNKDKLKE YLKFHVIRDA KVLAVDLPTS TAWKTLQGSE LSVKCGAGRD I
Positive Samples: HepG2, BT-474, Mouse liver, Mouse eye, Mouse kidney, Rat liver
Cellular Location: Cell membrane, Cytoplasm, Single-pass type I membrane protein
Target Information
This gene encodes a large transmembrane receptor protein involved in angiogenesis, lymphocyte homing, cell adhesion, and receptor scavenging. It contains multiple fasciclin, EGF-like, and laminin-type domains, as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of the liver, spleen, and lymph node. It binds and endocytoses ligands such as hyaluronan, low-density lipoprotein, bacteria, and advanced glycosylation end products, supporting its role as a scavenger receptor cycling between the plasma membrane and lysosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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