Thermo Fisher Scientific NACA Polyclonal Antibody, MaxPab
Thermo Fisher Scientific의 NACA 폴리클로날 항체는 인간 NACA 단백질을 표적으로 하는 연구용 항체로, WB 및 ICC/IF 분석에 적합합니다. 액상 형태이며 친화성 크로마토그래피로 정제되었습니다. PBS 버퍼에 보존제가 없으며 -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
- Immunocytochemistry (ICC/IF): 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | NACA (NP_005585.1, 1–215 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MPGEATETVP ATEQELPQPQ AETGSGTESD SDESVPELEE QDSTQATTQQ AQLAAAAEID EEPVSKAKQS RSEKKARKAM SKLGLRQVTG VTRVTIRKSK NILFVITKPD VYKSPASDTY IVFGEAKIED LSQQAQLAAA EKFKVQGEAV SNIQENTQTP TVQEESEEEE VDETGVEVKD IELVMSQANV SRAKAVRALK NNSNDIVNAI MELTM
Target Information
NACA prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). It binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER.
NACA also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites), and may act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: H00004666-B01P_NACA_Q13765-1_House_mouse.svg, H00004666-B01P_NACA_Q13765-1_House_mouse_PDP.jpeg)
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