
Thermo Fisher Scientific NAB2 Polyclonal Antibody, MaxPab
NAB2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 적합합니다. 인간 시료 반응성이 있으며, PBS(pH 7.4) 용액 형태로 제공됩니다. 핵 내 전사 조절 연구 및 Egr-1/NGFI-A 관련 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | NAB2 (AAH07756.1, 1 a.a. ~ 241 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MHRAPSPTAE QPPGGGDSAR RTLQPRLKPS ARAMALPRTL GELQLYRVLQ RANLLSYYET FIQQGGDDVQ QLCEAGEEEF LEIMALVGMA TKPLHVRRLQ KALREWATNP GLFSQPVPAV PVSSIPLFKI SETAGTRKGS MSNGHGSPGE KAGSARSFSP KSPLELGEKL SPLPGGPGAG DPRIWPGRST PESDVGAGGE EEAGSRWDWG WSRPTGARDG TPACLGRVWM DICRLWGHVQ G
Target Information
Transcriptional control is regulated by interactions between DNA-bound transcription factors (such as Egr-1/NGFI-A) and coregulatory proteins (such as NAB family proteins). NAB1 and NAB2 are evolutionarily conserved corepressors of EGF-1/NGFI-A.
- NAB2 localizes primarily in the nucleus.
- Plays a role in downregulating NGFI-A activity.
- Involved in fundamental processes such as cell division, differentiation, and apoptosis.
- Predicted molecular mass: 56 kDa
- Chromosomal location: 12q13.3–14.1 (region rearranged in several solid tumors, lipomas, and liposarcomas)
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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