Thermo Fisher Scientific Synapsin 1 Polyclonal Antibody

Thermo Fisher Scientific Synapsin 1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• This antibody has little or no activity against Synapsin II.
• Storage and reconstitution:
  When stored at -20°C or below, the lyophilized antibody retains full activity for over one year.
  Reconstitute using 50 µL PBS (pH 7.4) to yield a 0.2 mg/mL solution.
  If storing at 0–4°C, add sodium azide to a final concentration of 2 mM.
  For long-term storage, divide into aliquots and freeze at -20°C, avoiding freeze/thaw cycles.

Target Information

SYN1 (Synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. These proteins play roles in synaptogenesis and neurotransmitter release modulation, suggesting involvement in neuropsychiatric diseases. Synapsin 1 regulates axonogenesis and synaptogenesis and serves as a substrate for multiple protein kinases. Mutations in this gene may be linked to X-linked neuronal degeneration disorders such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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