Thermo Fisher Scientific ADAMTS13 Polyclonal Antibody
ADAMTS13 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, ICC/IF에 사용 가능. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제. 액상 형태, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific ADAMTS13 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ADAMTS13 (Accession Q76LX8), corresponding to amino acid residues S1162–D1212 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852913 |
Product Specific Information
Antibody detects endogenous levels of total ADAMTS13.
Target Information
ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
The enzyme is the von Willebrand Factor (vWF)-cleaving protease, responsible for cleaving at the site of Tyr842–Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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