Thermo Fisher Scientific CD104 Recombinant Rabbit Monoclonal Antibody (ARC1046)
CD104 (Integrin beta 4) 단백질을 인식하는 재조합 토끼 단일클론 항체로, WB 및 ELISA에 적합합니다. HEK293 세포에서 발현되었으며, 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
- ELISA: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1046 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1604–1822 of human ITGB4 (P16144) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849441 |
Product Specific Information
Immunogen sequence:
SQEGWGRERE GVITIESQVH PQSPLCPLPG SAFTLSTPSA PGPLVFTALS PDSLQLSWER PRRPNGDIVG YLVTCEMAQG GGPATAFRVD GDSPESRLTV PGLSENVPYK FKVQARTTEG FGPEREGIIT IESQDGGPFP QLGSRAGLFQ HPLQSEYSSI TTTHTSATEP FLVDGLTLGA QHLEAGGSLT RHVTQEFVSR TLTTSGTLST HMDQQFFQT
Target Information
Integrins are heterodimers composed of alpha and beta subunits that form noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides create complexes with varying ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion and transduce signals regulating gene expression and cell growth.
The ITGB4 gene encodes the integrin beta 4 subunit, a receptor for laminins, which associates with the alpha 6 subunit and plays a key role in invasive carcinoma biology. Mutations in this gene are linked to epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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