Thermo Fisher Scientific CD104 Recombinant Rabbit Monoclonal Antibody (ARC1046)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC1046

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1604-1822 of human ITGB4 (P16144) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD104 (Integrin beta 4),uniProtId:P16144-1,ncbiNodeId:9606,antigenRange:1604-1822,antigenLength:1822,antigenImageFileName:MA5-35541_CD104_Integrin_beta_4_P16144-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35541_CD104_Integrin_beta_4_P16144-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849441

Product Specific Information

Immunogen sequence: SQEGWGRERE GVITIESQVH PQSPLCPLPG SAFTLSTPSA PGPLVFTALS PDSLQLSWER PRRPNGDIVG YLVTCEMAQG GGPATAFRVD GDSPESRLTV PGLSENVPYK FKVQARTTEG FGPEREGIIT IESQDGGPFP QLGSRAGLFQ HPLQSEYSSI TTTHTSATEP FLVDGLTLGA QHLEAGGSLT RHVTQEFVSR TLTTSGTLST HMDQQFFQT

Target Information

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.