Thermo Fisher Scientific GluR4 Recombinant Rabbit Monoclonal Antibody (ARC1045)
GluR4 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. 마우스와 랫트 시료에 반응하며, HEK293 세포에서 발현되었습니다. 고순도의 친화 크로마토그래피 정제 제품으로, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1045 |
| Immunogen | A synthetic peptide corresponding to amino acids 800–902 of human GluR4/GluA4/GRIA4 (UniProt ID: P48058) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.84 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849440 |
Product Specific Information
Immunogen sequence:
SGSKDKTSAL SLSNVAGVFY ILVGGLGLAM LVALIEFCYK SRAEAKRMKL TFSEAIRNKA RLSITGSVGE NGRVLTPDCP KAVHTGTAIR QSSGLAVIAS DLP
Target Information
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development, and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. These receptors are primarily responsible for fast excitatory neurotransmission by glutamate, while NMDA receptors are characterized by slower kinetics and higher Ca²⁺ permeability.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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