Thermo Fisher Scientific UBF-1 Polyclonal Antibody
UBF-1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, HepG2 핵추출물에서 양성 대조로 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 용액 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human UBTF. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2736763 |
Product Specific Information
- Positive Control: HepG2 nuclear extract
- Predicted Reactivity: Mouse (100%), Rat (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
UBF-1 encodes a member of the HMG-box DNA-binding protein family.
The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions.
It may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by phosphorylation and acetylation.
Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Pseudogenes of this gene are located on the short arm of chromosomes 3, 11, and X, and the long arm of chromosome 11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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