Thermo Fisher Scientific PPP1R7 Monoclonal Antibody (OTI3E7), TrueMAB
PPP1R7 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체로, Western blot에 적합. 인간 및 개 반응성. HEK293T 세포에서 생산된 재조합 단백질을 면역원으로 사용. 액상 형태, 1.5 mg/mL 농도, -20°C 보관.
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Thermo Fisher Scientific PPP1R7 Monoclonal Antibody (OTI3E7), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Species Reactivity
- Dog
- Human
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E7 |
| Immunogen | Full length human recombinant protein of human PPP1R7 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase 1 (PP1) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit.
Sds22, also known as PPP1R7 (protein phosphatase 1, regulatory (inhibitor) subunit 7), is a 360 amino acid protein that localizes to the nucleus and contains ten LRR (leucine rich) repeats. Expressed in a variety of tissues, Sds22 functions as a regulatory subunit of the PP1 complex, suggesting a role in protein regulation throughout the cell. Multiple isoforms of Sds22 exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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