Thermo Fisher Scientific SMC4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SMC4 (NP_0012756821) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SMC4,uniProtId:Q9NTJ3-1,ncbiNodeId:9606,antigenRange:1-100,antigenLength:1288,antigenImageFileName:PA5-89539_SMC4_Q9NTJ3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89539_SMC4_Q9NTJ3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.15 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805637

Product Specific Information

Immunogen sequence: MPRKGTQPST ARRREEGPPP PSPDGASSDA EPEPPSGRTE SPATAAAMTN EAGAPRLMIT HIVNQNFKSY AGEKILGPFH KRFSCIIGPN GSGKSNVIDS; Positive Samples: HT-29, MCF7, Raji, HeLa; Cellular Location: Chromosome, Cytoplasm, Nucleus

Target Information

The proteins belonging to structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins that form two distinct heterodimeric complexes in the cell, the human chromosome-associated protein (hCAP)-C and hCAP-E protein complex (hCAP-C/hCAP-E), and the human SMC1 (hSMC1) and hSMC3 protein complex (hSMC1/hSMC3) have been identified.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.