Thermo Fisher Scientific CYP4F3 Polyclonal Antibody
CYP4F3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 인간 시료에 반응하며, Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관되며, -20°C에서 안정적.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CYP4F3 (Accession Q08477), corresponding to amino acid residues G65–A115 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852740 |
Product Specific Information
This antibody detects endogenous levels of total Cytochrome P450 4F3.
Target Information
Cytochrome P450 superfamily proteins are monooxygenases that catalyze various biochemical reactions involved in drug metabolism and the synthesis of cholesterol, steroids, and lipids.
CYP4F3, a 60 kDa protein, is a member of this family with a conserved heme-binding domain near the C-terminus. It catalyzes the ω-hydroxylation of LTB4 and is localized in the endoplasmic reticulum, playing a vital role in LTB4 inactivation and inflammation control.
CYP4F3 exists in two functionally distinct isoforms:
- CYP4F3A: A neutrophil isoform expressed in neutrophils and myeloid cells; catalyzes microsomal ω-hydroxylation of LTB4 and interacts with CD11b and myeloperoxidase to regulate cellular development in bone marrow.
- CYP4F3B: A liver isoform that converts arachidonic acid to 20-HETE, a potent PKC activator involved in cell proliferation, vascular tone, and natriuresis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific COX8C Polyclonal Antibody
627,600원
Thermo Fisher Scientific
Thermo Fisher Scientific CYP4F8 Polyclonal Antibody
627,600원
Thermo Fisher Scientific
Thermo Fisher Scientific CYP4F3 Polyclonal Antibody
627,600원
Thermo Fisher Scientific
Thermo Fisher Scientific CDH26 Polyclonal Antibody
627,600원
Thermo Fisher Scientific
Thermo Fisher Scientific COX7C Polyclonal Antibody
627,600원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|