Thermo Fisher Scientific TRPC1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 400-500 of human TRPC1 (NP_001238774.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TRPC1,uniProtId:P48995-1,ncbiNodeId:9606,antigenRange:400-500,antigenLength:793,antigenImageFileName:PA5-110525_TRPC1_P48995-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110525_TRPC1_P48995-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855936

Product Specific Information

Immunogen sequence: LLNLYSLVYN EDKKNTMGPA LERIDYLLIL WIIGMIWSDI KRLWYEGLED FLEESRNQLS FVMNSLYLAT FALKVVAHNK FHDFADRKDW DAFHPTLVAE G

Target Information

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Interacts with ITPR3. Appears to be ubiquitous.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.